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ISIOS+ is a synthetic bone substitute with exceptionally high porosity (90%) and total interconnection. Thanks to this porosity and its chemical composition (beta-
TCP), when implanted in bone, ISIOS+ is replaced in 6 or 7 months by neoformed bone tissue.
- Sinus graft
- Bone loss correction
- Alveolar filling
- Periodontology
ISIOS+is entirely composed of beta-TCP. Beta-TCP, or beta-tricalcium phosphate, belongs to the same chemical family as the mineral substance of bone, so that
osseointegration is complete when it is placed in a bone site.
Global ISIOS+ porosity is close to 90%. Both macroporosity and microporosity are present. The macroporous component is made up of largesized pores (0.2 to
0.5 mm), all interconnected. This interconnected macroporosity allows bone tissue to penetrate into the heart of the biomaterial (osseointegration by osseoconduction).
The next step is the start of the ISIOS+ bone remodeling process, during which bone cells will be fragmenting and digesting the biomaterial while they produce
new bone replacement tissue.

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